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Image Search Results
Journal: Frontiers in Immunology
Article Title: Mapping Salivary Proteases in Sjögren’s Syndrome Patients Reveals Overexpression of Dipeptidyl Peptidase-4/CD26
doi: 10.3389/fimmu.2021.686480
Figure Lengend Snippet: Detection of human MMP9 in the saliva from Sjögren’s syndrome individuals. The MMP9 concentration was measured in all saliva samples [ (A) ; Mann–Whitney test] and between SS groups [ (B) ; Kruskal–Wallis test] with the Human MMP9 DuoSet ELISA kit (R&D Systems, USA) according to the manufacturer’s instructions.
Article Snippet: The DPP4/CD26 and the MMP9 concentrations were measured with the Human DPP4/CD26 DuoSet (DY1180) and
Techniques: Concentration Assay, MANN-WHITNEY, Enzyme-linked Immunosorbent Assay
Journal: Frontiers in Immunology
Article Title: Mapping Salivary Proteases in Sjögren’s Syndrome Patients Reveals Overexpression of Dipeptidyl Peptidase-4/CD26
doi: 10.3389/fimmu.2021.686480
Figure Lengend Snippet: Immunoassay measurements for MMP9 and DPP4/CD26 illustrate the interdependence between these proteases in the saliva from pSS individuals. Analysis of correlation of MMP9 concentrations with those of DPP4/CD26 in control (A) ; pSS: primary Sjögren’s syndrome (B, D, E) ; and sSS: secondary Sjögren’s syndrome (C, F, G) individuals. AI, anti-inflammatory drugs use; No AI, no anti-inflammatory drugs use; IS, immunosuppressive drugs use; No IS, no immunosuppressive drugs use.
Article Snippet: The DPP4/CD26 and the MMP9 concentrations were measured with the Human DPP4/CD26 DuoSet (DY1180) and
Techniques: Control
Journal: Journal of Inflammation Research
Article Title: Identification of Neutrophil Extracellular Trap-Related Gene Expression Signatures in Ischemia Reperfusion Injury During Lung Transplantation: A Transcriptome Analysis and Clinical Validation
doi: 10.2147/jir.s444774
Figure Lengend Snippet: Figure 6 Validation of the diagnostic values of the key genes. (A) Differential expression of four key genes between the ischemic and reperfused lung allografts based on the merged dataset. ***p<0.001. (B) Differential expression of four key genes between the ischemic and reperfused lung allografts based on external dataset GSE18995. ***p<0.001. (C) ROC curves for the validation of FCAR, MMP9, PADI4, and S100A12 based on external dataset GSE18995.
Article Snippet: ELISA kits for S100A12 (CSB-E13095h), PADI4 (CSB-E16219h) and
Techniques: Biomarker Discovery, Diagnostic Assay, Quantitative Proteomics
Journal: Journal of Inflammation Research
Article Title: Identification of Neutrophil Extracellular Trap-Related Gene Expression Signatures in Ischemia Reperfusion Injury During Lung Transplantation: A Transcriptome Analysis and Clinical Validation
doi: 10.2147/jir.s444774
Figure Lengend Snippet: Figure 7 Construction and validation of a nomogram model for IRI diagnosis. (A) The nomogram of diagnostic biomarkers to predict the occurrence of IRI. (B) The ROC curve of nomogram model to predict IRI diagnostic value. (C) The ROC curve of each candidate hub gene (PADI4, MMP9, S100A12, and FCAR) to predict IRI diagnostic value. (D) The calibration curve to assess the predictive power of the nomogram model. (E) The DCA curve to evaluate the clinical application value of nomogram model. (F) Clinical impact curves of the nomogram model.
Article Snippet: ELISA kits for S100A12 (CSB-E13095h), PADI4 (CSB-E16219h) and
Techniques: Biomarker Discovery, Diagnostic Assay
Journal: Journal of Inflammation Research
Article Title: Identification of Neutrophil Extracellular Trap-Related Gene Expression Signatures in Ischemia Reperfusion Injury During Lung Transplantation: A Transcriptome Analysis and Clinical Validation
doi: 10.2147/jir.s444774
Figure Lengend Snippet: Figure 9 Validation of clinical samples. (A) Immunofluorescence microscopy showing neutrophil extracellular traps, defined as SYTOX Green (green), histone (red), and colocalized extracellular DNA (blue), present in lungs allograft after reperfusion. Scale bar = 130 μm. Results are representative of at least three independent experiments. (B) The levels of dsDNA in the plasma of patients undergoing lung transplantation. *p<0.05, ***p<0.001. (C–E) The levels of MMP9, PADI4, and S100A12 in the plasma of patients undergoing lung transplantation. *p<0.05, ***p<0.001. (F) Correlation analysis between dsDNA and MMP9 expression levels. (G) Correlation analysis between dsDNA and PADI4 expression levels. (H) Correlation analysis between dsDNA and S100A12 expression levels.
Article Snippet: ELISA kits for S100A12 (CSB-E13095h), PADI4 (CSB-E16219h) and
Techniques: Biomarker Discovery, Immunofluorescence, Microscopy, Clinical Proteomics, Transplantation Assay, Expressing